A DELETERIOUS NAV1.1 MUTATION SELECTIVELY IMPAIRS TELENCEPHALIC INHIBITORY NEURONS DERIVED FROM DRAVET SYNDROME PATIENTS

A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients

Dravet Syndrome is an intractable form of childhood epilepsy associated with deleterious mutations Oral Care in SCN1A, the gene encoding neuronal sodium channel Nav1.1.Earlier studies using human induced pluripotent stem cells (iPSCs) have produced mixed results regarding the importance of Nav1.1 in human inhibitory versus excitatory neurons.We stu

read more

The Association between a MAOB Variable Number Tandem Repeat Polymorphism and copyright and Opiate Addictions in Polyconsumers

Genetic analysis of the association between alcohol, copyright, and opiate addiction and variable number tandem repeat (VNTR) polymorphisms in monoamine oxidase B (MAOB) and serotonergic 5-hydroxytryptamine (serotonin) receptor 1B and 2C (HTR1B Bags 21 and HTR2C) pathway genes was performed in a sample of 302 polyconsumers.Our genetic association a

read more